We have developed novel imaging methods to obtain advanced measures of cardiovascular function. These measures have provide insight into the contractility of the heart as well as regional variations in function.
Pressure-Volume Loop Quantification
Real-time MRI imaging techniques we developed allowed for quick variations loading conditions to be performed. This allowed for estimates of contractility to be obtained from Pressure-Volume loops and Frank-Starling relations.
The complex pattern of the endocardial surface can be visualized and tracked over time using cineCT. This allows for estimation of regional changes in surface area. With this tracking, we have derived measures of regional myocardial contractility.